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Welcome to Grapevine Cafe

This Is Your Taste of Donaldsonville

We invite you to experience Grapevine Cafe’s award winning cuisine, a unique blend of Cajun, Creole and African traditions.

The Grapevine Experience

Louisiana flavor
A place to gather

Come for the Cajun and Creole cooking. Stay for the art, the music, and the warm welcome.

Within the walls of a restored building dating to the 1920s in historic downtown Donaldsonville, authentic South Louisiana cuisine meets rotating collections of local art and the sounds of area musicians. We welcome locals and visitors from New Orleans, Baton Rouge, and beyond.

  • Cajun & Creole
  • Local art
  • Local music
View the menu
Guests dining beside the tall windows in Grapevine Cafe's historic dining room
A plate of Louisiana cuisine served at Grapevine Cafe

At home in Donaldsonville since 2001.

Colorful cocktails and wines at Grapevine Cafe

Good Drinks. Great Times.

Happy Hour

Thursdays & Fridays · 2–5 PM CT

$10Select Martinis

BOGOHouse Wines

$8Specialty Cocktails

Bring good company. We’ll take care of the drinks and appetizers.

Join us at Grapevine

A table worth
gathering around

Reservations are highly recommended. Reserve your table online, or give us a call for assistance.

211 Railroad Avenue Donaldsonville, LA

From our menu to your table

Found your favorite?
Come enjoy it with us

Reservations are highly recommended. Reserve online, or give us a call for assistance.

Find us

Come on over

A little Louisiana hospitality, right in historic downtown Donaldsonville.

Grapevine Cafe & Gallery211 Railroad Avenue
Donaldsonville, LA 70346

Happy Hour

Good Drinks. Great Times.

Thursdays & Fridays only 2–5 PM Central Time

Colorful martinis, cocktails and wine on the Grapevine Cafe bar

$10

Select Martinis

View martinis
  • Lemon Drops Classic, Redberry, Blue Raspberry & Blueberry
  • Classic or Dirty Gin or vodka
  • Cosmo
  • Chocolate
  • Praline Espresso

BOGO

House Wines

Buy one, get one.
A little more to toast to.

$8

Specialty Cocktails

View cocktails
  • Old Fashioneds
  • Margarita
  • Bahama Mama
  • Strawberry Hennessy Lemonade

Come for the drinks. Stay for a bite.

The full appetizer menu + Happy Hour exclusive appetizers are the only food items available during Happy Hour.

Good to know · seating, upgrades & dine-in details

Your favorites, your wayDiscounts apply to select drinks; the full bar is available. Premium liquor upgrades are available for an additional fee.

A little note on seatingTables may only be available for a limited time due to upcoming dinner reservations. Please ask staff about any restrictions.

Dine in onlyNo to-go orders or rainchecks on BOGO items.

Great Drinks. Good Company. The Grapevine.

Thank you! We appreciate your understanding and support.

Plan your visit

Opening hours

Regular opening hours

Donaldsonville, Louisiana · Central Time

Weekly opening hours in Central Time

Based on our regular weekly hours. Holiday hours and special closures may vary.

Call (225) 473-8463

Grapevine Cafe

Grilled steak topped with crabmeat, served with mashed potatoes and green beans